The main source of androgens will come from the zona reticularis region.
2.
Pyknotic nuclei are often found in the zona reticularis of the adrenal gland.
3.
Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone ( DHEA ) and androstenedione from cholesterol.
4.
In the zona reticularis layer of the adrenal cortex, DHEA-sulfate is generated by SULT2A1.
5.
The adrenal cortex itself is divided into three zones : zona glomerulosa, the zona fasciculata and the zona reticularis.
6.
Androgens, or sex hormones, are synthesized in the innermost layer of the adrenal cortex known as the zona reticularis.
7.
Synthesis takes place in the zona fasciculata of the adrenal cortex . ( The name cortisol is derived from cortex . ) While the adrenal cortex also produces aldosterone ( in the zona glomerulosa ) and some sex hormones ( in the zona reticularis ), cortisol is its main secretion in humans and several other species . ( However, in cattle, corticosterone levels may approach or exceed cortisol levels . ).
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